abstract：:Plasma cholesterol was lower in spontaneously hypertensive rats (SHR), while plasma triglyceride and free fatty acid were increased in comparison with control normotensive Wistar-Kyoto (WK) rats. Correspondingly, [1-14C]-acetate incorporation into liver cholesterol was clearly decreased in SHR as compared with WK. As ...

journal_title：Atherosclerosis

authors： Iritani N,Fukuda E,Nara Y,Yamori Y

更新日期：1977-11-01 00:00:00

abstract：:Rats were fed for 24 days a liquid diet with ethanol as 36% of calories to produce hyperlipemia and hepatic steatosis. The catabolism of chylomicrons doubly-labeled in the triacylglycerol and cholesteryl ester moieties was studied in conscious rats after ingestion of their usual liquid diets with or without ethanol. A...

journal_title：Atherosclerosis

authors： Redgrave TG,Martin G

更新日期：1977-09-01 00:00:00

abstract：:Measurements of aortic length and circumference in 336 post-mortem specimens confirm earlier, neglected observations on the progressive increase in aortic size which occurs with advancing years. The increase is not related to atherosclerosis , or to hypertension and seems to be part of a true ageing process. The value...

journal_title：Atherosclerosis

authors： Mitchell JR,Adams JH

更新日期：1977-08-01 00:00:00

abstract：:Randomized lard and butter oil were conpared with native lard and butter oil for their effects on cholesterol-induced atherosclerosis in rabbits. In each experiment there was also a group fed corn oil. The diets contained 2% cholesterol and 6% fat and were fed for eight weeks. Randomization of either butter or lard ha...

journal_title：Atherosclerosis

authors： Kritchevsky D,Tepper SA

更新日期：1977-07-01 00:00:00

abstract：:Hyaluronate (HA), heparan sulfate (HS), dermatan sulfate (DS) and isomeric chondroitin sulfates (CS) were measured in vascular walls of 9-10 months old normal and hypophysectomized female beagles treated with sex hormones. Following hypophysectomy the animals were maintained for 8 weeks without any hormonal replacemen...

journal_title：Atherosclerosis

authors： Sirek OV,Sirek A,Fikar K

更新日期：1977-06-01 00:00:00

abstract：:Male and female rats kept on a long-term atherogenic regimen for periods up to 15 months developed marked atherosclerotic changes of cardiac valves in 100% of cases. The degree and the topography of valvular atherosclerotic plaques corresponded widely to that seen in human atherosclerotic valvular disease. The regular...

journal_title：Atherosclerosis

authors： Záhor Z,Czabanová V

更新日期：1977-05-01 00:00:00

abstract：:The ontogenic development of lipoprotein lipase and liver triglyceride hydrolase was studied in the rat. The enzyme activity measured in extrahepatic tissues fulfilled the criteria of lipoprotein lipase from the onset of measurable activity, i.e. it was inhibited by protamine and 1 M NaCl and showed requirement for se...

journal_title：Atherosclerosis

authors： Chajek T,Stein O,Stein Y

更新日期：1977-04-01 00:00:00

abstract：:The hydrolysis of lipoprotein triglycerides is catalyzed by lipoprotein lipase (LPL), an enzyme found in many tissues. We have examined tissue LPL activity (LPLA) in rats with experimentally-induced hyperthyroidism. In younger, lighter rats, hyperthyroidism was accompanied by a decrease in LPL in adipose tissue wherea...

journal_title：Atherosclerosis

authors： Wilson DE,Jubiz W,Flowers CM,Carlile SI,Adolf AM

更新日期：1977-03-01 00:00:00

abstract：:Hypertension is associated with an increased incidence of generalized vascular disease. Antihypertensive drug therapy, while decreasing overall mortality due to cerebral hemorrhage, myocardial hypertrophy or renal failure, paradoxically does not appear to reduce the incidence of coronary atherosclerosis. This study in...

journal_title：Atherosclerosis

authors： Bailey JM,Randazzo R

更新日期：1977-01-01 00:00:00

abstract：:The composition of very low density lipoproteins (VLDL: d less than 1.019) of New Zealand male rabbits reciving cholesterol (2 g/day) and metformin (135 mg/kg/day) is investigated. These rabbits, while showing only a slight reduction of plasma cholesterol levels, as compared to cholesterol-fed (h.c.) animals, show a m...

journal_title：Atherosclerosis

authors： Sirtori CR,Catapano A,Ghiselli GC,Innocenti AL,Rodriguez J

更新日期：1977-01-01 00:00:00

abstract：:Incorporation of 125I-labeled cholesterol ester rich lipoproteins from cholesterol fed rabbits into normal rabbit aorta in vitro was inhibited by heparin, lecithin, and collagenase and by succinylation of the lipoprotein. Aortic uptake of lipoprotein was increased by neuraminidase, proteases, lipase, and beta-glucuron...

journal_title：Atherosclerosis

authors： Day CE

更新日期：1976-11-01 00:00:00

abstract：:The effect of methyl prednisolone and colchicine on the development of both the early proliferative and advanced atherosclerotic lesion in swine aorta was studied. In order to accelerate the development of atherosclerosis, the abdominal aortic endothelium was partially denuded by a balloon before the animals were plac...

journal_title：Atherosclerosis

authors： Lee WM,Morrison ES,Scott RF,Lee KT,Kroms M

更新日期：1976-11-01 00:00:00

abstract：:Electrocardiographic and cardiovascular responses during maximal exercise were evaluated in 103 normal children and in 82 children with familial hyperlipoproteinemia. The normal and hyperlipidemic children were comparable in regards to age, weight--height index, resting and exercise blood pressures, and maximal workin...

journal_title：Atherosclerosis

authors： James FW,Glueck CJ,Fallat RW,Millett F,Kaplan S

更新日期：1976-10-01 00:00:00

abstract：:Polar coordinate mapping was used to determine the rate of growth of individual sudanophilic lesions on the aortic wall around several major branches of the aortae of cholesterol fed rabbits. Four groups, with 6 8-month old male albino white rabbits in each, were used in the study. One group served as a control and th...

journal_title：Atherosclerosis

authors： Roach MR,Fletcher J,Cornhill JF

更新日期：1976-10-01 00:00:00

abstract：:Increased aortic and liver prolyl hydroxylase activity has been suggested as an early biochemical indicator of the fibrotic changes which occur in rabbits with injury induced arteriosclerosis. Daily administration of epinephrine (0.025-0.050 mg/kg, i.v.) and thyroxine (0.050 mg/kg, i.p.) to rabbits for 3 weeks produce...

journal_title：Atherosclerosis

authors： Fuller GC,Matoney AL,Fisher DO,Fausto N,Cardinale GJ

更新日期：1976-09-01 00:00:00

abstract：:The effectiveness of a new, almost l-thyroxine free preparation of d-thyroxine (Dynothel) was tested in 15 patients with Type IIa and 4 patients with Type IIb hyperlipoproteinemia. Eleven patients with Type IIa and 3 with Type IIb were responsive to treatment and showed an average 26% decrease in plasma TC. This decre...

journal_title：Atherosclerosis

authors： Rakow AD,Klor HU,Kuter E,Ditschuneit HH,Ditschuneit H

更新日期：1976-09-01 00:00:00

abstract：:The effect of short-term dietary restriction on plasma cholesterol and cholesterol balance was examined in young While Carneau pigeons. Dietary restriction of 1 month increased plasma cholesterol significantly and subsequently decreased to initial levels at 3 months. The fecal excretion of neutral sterols was signific...

journal_title：Atherosclerosis

authors： Subbiah MT,Connelly PW

更新日期：1976-09-01 00:00:00

abstract：:A solid phase radioimmunoassay (RIA) has been developed for apolipoprotein B (apoB), a major constituent of very low density lipoprotein (VLDL) and low density lipoprotein (LDL) in man. Antisera were prepared against apoB in goats and rabbits, coupled to bromoacetyle cellulose, and the complex was incubated with [125I...

journal_title：Atherosclerosis

authors： Thompson GR,Birnbaumer ME,Levy RI,Gotto AM Jr

更新日期：1976-07-01 00:00:00

abstract：:Baroreceptor sensitivity was studied in twelve young normotensive subjects and forty hypertensive patients, separated into two groups according to their age, severity of hypertension and signs of severe atherosclerotic vascular disease. Under stabilized circulatory conditions, the changes of pulse rate in response to ...

journal_title：Atherosclerosis

authors： Vlachakis ND,Mendlowitz M,DGuia D,DGusman D

更新日期：1976-07-01 00:00:00

abstract：:External jugular veins that had been subjected to the hemodynamic stresses produced by experimental arteriovenous anastomosis developed 2% increased total protein contents and 17% increased collagen contents. When the stressed veins were homogenized and extracted with saline solutions, statistically significant increa...

journal_title：Atherosclerosis

authors： Smith RA,Stehbens WE,Weber P

更新日期：1976-05-01 00:00:00

abstract：:The aortic endothelium of rabbits fed a stock diet containing 1 or 2% cholesterol for intervals of 1 day to 21 weeks was compared with that of normal rabbits on a stock diet without cholesterol. The endothelium was examined en face using the Häutchen technique. The aortic endothelium of the experimental animals reveal...

journal_title：Atherosclerosis

authors： Silkworth JB,McLean B,Stehbens WE

更新日期：1975-11-01 00:00:00

abstract：:The effect of renal hypertension on dry defatted tissue mass and lipid accumulation in different segments of the aortic intima was studied in both normally-fed and cholesterol-fed rabbits. In normally-fed rabbits hypertension caused an increase in intimal dry weight in the aorta. The increase was greatest in the lower...

journal_title：Atherosclerosis

authors： Bretherton KN,Day AJ,Skinner SL

更新日期：1975-11-01 00:00:00

abstract：:A comparative study was made of 36 aortic enzyme activities (E.A.) and 6 macromelecular substances at different stages of ontogenesis in 49 male rats. In the foetal aorta (19th day) the E.Z. were moderate or weak and restricted to a few metabolic pathways: glycolysis, diaphorases, esterolysis of some nucleotides and g...

journal_title：Atherosclerosis

authors： Hadjiisky P,Renais J,Scebat L

更新日期：1975-07-01 00:00:00

abstract：:The dose-response effects of clofibrate and niceritrol on serum cholesterol and triglycerides (TG) were studied in 29 patients with Type IIa and IIb hyperlipoproteinaemia. In 17 patients, clofibrate and niceritrol were then given as combined treatment, and the effects of this combination on serum lipoproteins were stu...

journal_title：Atherosclerosis

authors： Olsson AG,Orö L,Rössner S

更新日期：1975-07-01 00:00:00

abstract：:Marked hypercholesterolemia and moderate lipid infiltration of the aorta were induced by feeding rabbits a diet containing 1% cholesterol + 3% corn oil for 70 days. In the liver the concentration and pool size of cholesterol increased and those of triglycerides (TG) decreased. On dietary addition of vitamin A and vita...

journal_title：Atherosclerosis

authors： Brattsand R

更新日期：1975-07-01 00:00:00

abstract：:We studied the effect of lysolecithin on the clearing of plasma cholesterol. The immediate and maximal conversion of plasma lecithin to lysolecithin was produced in rats by intravenous injection of phospholipase A. The changes which took place in the converted lysolecithin and of cholesterol were followed in rats whic...

journal_title：Atherosclerosis

authors： Dobiásová M,Faltová E,Marek J,Obenberger J

更新日期：1975-05-01 00:00:00

abstract：:Intact and ovariectomized, non-arteriosclerotic female rats and arteriosclerotic, breeder female rats were subjected to myocardial infarction by the administration of 2 subcutaneous injections, 24 hr apart, of the beta-adrenergic stimulator, isoproterenol. The animals were sacrificed at regular hourly intervals follow...

journal_title：Atherosclerosis

authors： Lewis BK,Wexler BC

更新日期：1975-05-01 00:00:00

abstract：:Histologic features of aortic fatty streaks were examined in male subjects aged 10-39 from Guatemala, Jamaica Negro, Durban Bantu, New Orleans Negro, New Orleans white, Lima and Santiago. These groups were selected from the 19 available in the IAP (International Atherosclerosis Project) because they represented the gr...

journal_title：Atherosclerosis

authors： Restrepo C,Tracy RE

更新日期：1975-03-01 00:00:00

abstract：SUMMARY:A type of spontaneous arteriosclerosis, described as medial sclerosis and quite distinct from atherosclerosis, was found in the aortas, coronary arteries and aortic branch arteries of free-living elephants (Loxodonta africana) in Uganda and Kenya. The lesions took the form of calcified fibrotic plaques in the i...

journal_title：Atherosclerosis

authors： McCullagh KG

更新日期：1975-01-01 00:00:00